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CBD and the Serotonin System: Exciting Possibilities Using CBD Oil

CBD’s ability to target a specific serotonin receptor, the serotonin 1A receptor, is associated with a remarkable range of therapeutic possibilities. Professor Roger Pertwee, a pharmacologist from the University of Aberdeen, spoke with Leafly about this aspect of CBD biology.

“It’s apparent ability to enhance the activation of serotonin 1A receptors supports the possibility that it could be used to ameliorate disorders that include: opioid dependence, neuropathic pain, depression and anxiety disorders, nausea and vomiting (e.g. from chemotherapy), and negative symptoms of schizophrenia,” he said. “One big unanswered question is what the human clinical relevance and importance of each of these potential therapeutic uses of CBD Oil, identified solely by examining data from non-human preclinical research, actually is.”

Given that these possibilities come mainly from animal studies, more research will be needed before we can think seriously about human applications.

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